A nationally recognized toxicology expert witness with more than 35 years of experience and retired academic leader, this expert specializes in biochemical and mechanistic toxicology involving drug-induced injury, chemical toxicity, pharmacokinetics, and molecular mechanisms of cellular damage. Areas of expertise include cell cycle regulators and cytokines as molecular targets in toxic injury; apoptosis and necrosis associated with toxic drugs and chemicals; drug and chemical biotransformation; pharmacokinetic alterations affecting toxicity; obesity- and nutrition-related effects on drug metabolism; genetic influences on toxicological response; and liver and kidney injury caused by pharmaceuticals and environmental chemicals. Additional experience includes in vitro toxicology, cultured cell systems, in vivo toxicology research, ion dysregulation in cell injury, DNA damage mechanisms, and toxicological evaluation involving hepatic and renal toxicity. The expert has provided toxicology consultations, deposition testimony, and courtroom testimony for more than 25 years involving toxic torts, impaired-driving toxicology, pharmaceutical toxicity, chemical exposure, and product liability matters. Professional appointments have included service as Professor Emeritus of Pharmaceutical Sciences, department chair, senior research advisor, graduate faculty member, and associate dean-level leadership responsibilities within colleges of pharmacy and health sciences. The expert has also served on multiple federal scientific advisory and toxicology review panels, including appointments associated with the United States Environmental Protection Agency and National Toxicology Program involving toxicological evaluation, carcinogenicity review, developmental neurotoxicity, pesticide toxicology, and human health risk assessment activities.

Widely published in the fields of toxicology, pharmacology, drug metabolism, and cellular injury, this expert has conducted extensive laboratory and translational research involving biochemical toxicology, molecular pharmacology, toxic mechanisms of drugs and environmental chemicals, obesity-related susceptibility to toxic injury, and metabolic factors influencing toxicological outcomes. Research and scientific investigation activities have included studies involving hepatotoxicity, nephrotoxicity, calcium-mediated cellular injury, reactive metabolites, programmed cell death, DNA fragmentation, cytochrome P450 systems, and pharmacological mechanisms underlying toxic responses. Additional experience includes leadership of NIH-funded and federally supported toxicology research projects, direction of graduate toxicology education and seminars, supervision of doctoral and postdoctoral trainees, and instruction in pharmacology, toxicology, biochemical toxicology, pollution toxicology, and drug metabolism. The expert has held numerous leadership positions within major toxicology and pharmacology organizations, including the Society of Toxicology, International Union of Toxicology, and related scientific associations, and has served on editorial boards and peer review activities for prominent toxicology and pharmacology journals. Professional credentials include designation as a Fellow of the Academy of Toxicological Sciences, together with extensive authorship of scientific publications, invited presentations, toxicology workshops, and scholarly contributions involving toxic injury mechanisms, pharmaceutical toxicology, environmental toxicology, and drug safety research. Educational attainment includes Bachelor’s, Master’s, and Doctor of Philosophy degrees in chemistry, pharmacology, biochemistry, toxicology, and related biomedical sciences, as well as postdoctoral fellowship training in pharmacology and toxicology.